Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Nature最新号
http://www.nature.com/nature/journal/v447/n7146/abs/nature05874_ja.html
何ともはや、すごいパワーあふれるレポート。

Surprisingly, many functional elements are seemingly unconstrained across mammalian evolution. This suggests the possibility of a large pool of neutral elements that are biochemically active but provide no specific benefit to the organism. This pool may serve as a 'warehouse' for natural selection, potentially acting as the source of lineage-specific elements and functionally conserved but non-orthologous elements between species.

ほほぅ。